Therapeutical method for the treatment of dermatoses using O-esters of L-carnitine
AssigneeAvantgarde S.p.A.
InventorsClaudio Cavazza, Paolo Cavazza
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Abstract
The use of O-esters of L-carnitine with saturated bicarboxylic acids (e.g. azelaic, sebacic, suberic and pimelic acid) or unsaturated monocarboxylic acids (e.g. linoleic, linolenic, oleic and orachidonic acid) is disclosed for producing pharmaceutical compositions suitable to be topically applied for treating dermatoses, such as ichthyosis and psoriasis.
Claims4
A therapeutical method for treating ichthyosis, psoriasis, dandruff, acne and palmar and plantar hyperkeratosis which comprises topically applying to the skin of a patient in need thereof a dermatologically effective amount of a L-carnitine ester having the formula (I) ##STR2## wherein R is an acyl group of
- (a) a saturated bicarboxylic acid selected from the group consisting of azelaic, sebacic, suberic and pimelic acid, or
- (b) an unsaturated monocarboxylic acid selected from the group consisting of linoleic, oleic and arachidonic acid;
- and
- X is the anion of a pharmacologically acceptable acid.
Dependencies are inferred from the claim text.