Synergistic antimicrobial compositions containing 2-(thiocyanomethylthio)benzothiazole and an organic acid
AssigneeBuckman Laboratories International, Inc.
InventorsDavid Oppong, C. George Hollis
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Abstract
Compositions comprising 2-(thiocyanomethylthio)benzothiazole and at least one organic acid or its salt are disclosed which are synergistically effective compared to the respective components alone in controlling the growth of microorganisms in or on a material or medium. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.
Claims24
A composition consisting essentially of (a) 2-(thiocyanomethylthio)benzothiazole and (b) at least one organic compound selected from the group consisting of benzoic acid, a salt thereof, p-hydroxybenzoic acid, a salt thereof, sodium benzoate, sodium 2-hydroxybenzoate, and mixtures thereof, wherein said components (a) and (b) are present in synergistic microbicidal effective amounts to control the growth of at least one microorganism selected from the group consisting of bacteria, fungi, and mixtures thereof.
A method of controlling the growth of at least one microorganism selected from the group consisting of bacteria and fungi in or on a material or medium susceptible to attack by the microorganism comprising the step of adding to the material or medium to control said growth a composition comprising synergistic microbicidal effective amounts of (a) 2-(thiocyanomethylthio)-benzothiazole and (b) at least one organic compound selected from the group consisting of benzoic acid, a salt thereof, p-hydroxybenzoic acid, a salt thereof sodium benzoate, sodium 2-hydroxybenzoate, and mixtures thereof.
A method for preventing spoilage of a material or medium caused by bacteria, fungi, or mixtures thereof comprising the step of adding to a material or medium to prevent spoilage a composition comprising synergistic microbicidal effective amounts of (a) 2-(thiocyanomethylthio)benzothiazole and (b) at least one organic compound selected from the group consisting of benzoic acid, a salt thereof, p-hydroxybenzoic acid, a salt thereof, sodium benzoate, sodium 2-hydroxybenzoate, and mixtures thereof.
Dependencies are inferred from the claim text.