Treatment of microbial infection with interleukin 1 polypeptides
AssigneeDainippon Pharmaceutical Co., Ltd.
InventorsMasaaki Yamada, Yasuji Furutani, Michiko Yamayoshi, Mitsue Notake, Junichi Yamagishi
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Abstract
DNAs encoding polypeptides having interleukin 1, vectors inserted with said DNAs, hosts transformed with said recombinant vectors, polypeptides having interleukin 1 activity which are produced by cultivation of the transformed hosts, derivatives of the polypeptides, pharmaceutical composition containing said polypeptides or derivatives, their use as an antitumor or antiinfectious agent, and processes for the preparation thereof.
Claims9
A method of treating a host for microbial infectious disease which comprises administering an amount effective to treat said disease of an isolated human interleukin 1.alpha. polypeptide wherein said polypeptide has an amino acid sequence selected from the group consisting of amino acids 113 to 271, 128 to 271 and 128 to 267 in FIG. 11.
Dependencies are inferred from the claim text.