Apparatus and methodology for determining oxygen in biological systems
AssigneeTrustees of Dartmouth College
InventorsHarold M. Swartz, Fuminori Goda, Tadeusz Walczak, Ke J. Liu
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AssigneeTrustees of Dartmouth College
InventorsHarold M. Swartz, Fuminori Goda, Tadeusz Walczak, Ke J. Liu
Estimating the term…
The invention provides apparatus and methods for measuring oxygen tensions in biological systems utilizing physiologically acceptable paramagnetic material, such as India ink or carbon black, and electron paramagnetic resonance (EPR) oximetry. India ink is introduced to the biological system and exposed to a magnetic field and an electromagnetic field in the 1-2 GHz range. The EPR spectra is then measured at the biological system to determine oxygen concentration. The EPR spectra is determined by an EPR spectrometer that adjusts the resonator to a single resonator frequency to compensate for movements of the biological system, such as a human or animal. The biological system can also include other in vivo tissues, cells, and cell cultures to directly measure pO.sub.2 non-destructively.
Apparatus for measuring oxygen tension in a biological system having a paramagnetic located therein, comprising
A system for determining oxygen tension within a biological system, comprising
A system for determining oxygen tension within a biological system, comprising
Dependencies are inferred from the claim text.