Certain pyridyl-benzopyran derivatives
AssigneeKorea Research Institute of Chemical Technology
InventorsSung-Eun Yoo, Kyu Y. Yi, Nak C. Jeong, Jee H. Suh, Seon-Ju Kim, Hwa-Sup Shin, Byung H. Lee, Kyu S. Jung
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AssigneeKorea Research Institute of Chemical Technology
InventorsSung-Eun Yoo, Kyu Y. Yi, Nak C. Jeong, Jee H. Suh, Seon-Ju Kim, Hwa-Sup Shin, Byung H. Lee, Kyu S. Jung
Estimating the term…
The present invention relates to novel benzopyran derivatives of formula (I) which have exellent effectiveness in the treatment of asthma as well as hypertension. ##STR1## wherein: R.sub.1 is --CN, --NO.sub.2, --OCX.sub.1 X.sub.2 X.sub.3, --NH.sub.2, --NHSO.sub.2 R.sup.A, ##STR2## --SO.sub.2 R.sup.C or --SO.sub.2 NR.sup.C R.sup.D wherein X.sub.1, X.sub.2 and X.sub.3 are, each independently, F, Cl or H, except for that X.sub.1, X.sub.2 and X.sub.3 may not be hydrogen atom simulaneously; R.sup.A and R.sup.B are, each independently, a hydrogen atom, or a C.sub.1-6 alkyl group or an optionally substituted phenyl group with a halogen atom, or a straight or branched C.sub.1-3 alkyl group; and R.sup.C and R.sup.D are, each independently, a hydrogen atom or a C.sub.1-6 alkyl group or an optionally substituted phenyl group with a halogen atom, or a straight or branched C.sub.1-3 alkyl group; R.sub.2 is a C.sub.1-4 straight or branched alkyl group; R.sub.3 is a C.sub.1-4 straight or branched alkyl group, ##STR3## wherein R.sup.G and R.sup.H are, each independently, a C.sub.1-6 alkyl group or optionally substituted phenyl group with a halogen atom, or a straight or branched C.sub.1-3 alkyl group, A and B are, each independently, S or O; X is N or N.fwdarw.O; Y is a hydrogen or halogen atom, or an amino, hydroxy, a lower alkoxy or lower alkyl group.
A novel benzopyran compound of formula (I) ##STR17## wherein:
Dependencies are inferred from the claim text.