Non-peptide tachykinin receptor antagonists to treat allergy
AssigneeEli Lilly and Company
InventorsBruce D. Gitter, William H. W. Lunn
Life of this patent
Estimating the term…
Abstract
This invention encompasses methods for the treatment or prevention of a physiological disorder associated with an excess of tachykinins, said disorder being an allergy which method comprises administering to a mammal in need of said treatment an effective amount of a compound of Formula I ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamthylenemino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Claims4
A method for the treatment or prevention of a physiological disorder associated with an excess of tachykinins, said disorder being an allergy which method comprises administering to a mammal in need of said treatment an effective amount of a compound of Formula I ##STR6## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR7## wherein Ar is optionally substituted phenyl;
- R.sup.2 is selected from the group consisting of pyrrolidine, hexamthylenemino, and piperidino;
- or a pharmaceutically acceptable salt of solvate thereof.
Dependencies are inferred from the claim text.