Lanoline derivatives as penetration enhancing substances
AssigneeLTS Lohmann Therapie-Systeme AG
InventorReinhard Von Kleinsorgen
Life of this patent
Estimating the term…
Abstract
Formulation to increase the transdermal permeation of pharmaceutical substances or other biologically active substances, characterized by a content of a penetration enhancing portion of lanoline derivatives on their own or in a mixture with esters of isopropyl alcohol with long-chain fatty acids and/or polyethyleneglycol ethers of fatty alcohols with longer chains, as penetration enhancing substances, as well as a process for their production.
Claims7
Formulation to increase the transdermal permeation of pharmaceutical substances or other biologically active substances, consisting essentially of a content of a penetration enhancing portion of lanolin derivatives alone or together with polyethylene glycol ethers of fatty alcohols as penetration enhancing substances,
- whereby the lanolin derivatives are selected from the group consisting of acetylated lanolin, acetylated lanolin alcohol, alkoxylated lanolin, lanolin acid, polyethoxylated lanolin acid, polyethoxylated lanolin alcohol, esters of lanolin acid with aliphatic alcohols, isopropyl lanolate and esters of lanolin alcohol with fatty acids.
Formulation for the administration through the skin consisting essentially of verapamile or gallopamile and for increasing the transdermal permeation lanolin derivatives, on their own or in a mixture with polyethyleneglycol ethers of fatty alcohols are contained therein as a penetration enhancing portion;
- and
- whereby the lanolin derivates are selected from the group consisting of acetylated lanolin, acetylated lanolin alcohol, alkoxylated lanolin, lanolin acid, polyethoxylated lanolin acid, polyethoxylated lanolin alcohols, esters of lanolin acid with aliphatic alcohols, isopropyl lanolate and esters of lanolin alcohol with fatty acids.
Dependencies are inferred from the claim text.