Back to results
US 5,491,284 AGranted
Nude mouse model for neoplastic disease
AssigneeAntiCancer, Inc.
InventorsAnn Monosov, Xinyu Fu
Life of this patent
Estimating the term…
Abstract
A nude mouse model for human neoplastic disease having histologically intact human neoplastic tissue transplanted onto an organ of the mouse which corresponds to the human organ from which the tissue is obtained.
Claims21
A nude mouse model for human neoplastic disease, wherein said mouse is characterized by:
- having histologically intact human neoplastic tissue of at least 1 mm.sup.3 in size transplanted onto an organ of said mouse which corresponds to the human organ from which said tissue is originally obtained;
- and
- having sufficient immuno-deficiency to allow said transplanted neoplastic tissue to grow and mimic the progression of the neoplastic disease in the human donor;
- wherein said human neoplastic tissue is selected from stomach, colon, pancreatic or lung tissue.
1 more element
A method of generating a nude mouse model for human neoplastic disease, said method comprising:
- transplanting histologically intact human neoplastic tissue of at least 1 mm.sup.3 in size onto an organ of a nude mouse which corresponds to the human organ from which said tissue is originally obtained;
- and
- allowing said transplanted tissue to grow and mimic progression of the neoplastic disease in the human donor;
- wherein said human neoplastic tissue is selected from stomach, colon, pancreatic or lung tissue.
1 more element
Dependencies are inferred from the claim text.