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US 5,491,243 AGranted
Intermediate useful for the asymmetric synthesis of duloxetine
AssigneeEli Lilly and Company
InventorRichard A. Berglund
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Abstract
This invention provides a stereospecific process for the synthesis of (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine, a key intermediate in the synthesis of duloxetine.
Claims1
(S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine, phosphoric acid salt.
Dependencies are inferred from the claim text.