Thiosemicarbazonethiones
AssigneeCiba-Geigy Corporation
InventorMartin Missbach
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Abstract
The invention relates to novel thiosemicarbazonethiones of formula (I) wherein R.sub.1 is lower alkyl, lower alk-2-en-1-yl or also lower alk-2-yn-1-yl, R.sub.2 and R.sub.3 are each independently of the other hydrogen or lower alkyl or, taken together, are lower alkylidene, R.sub.4 is hydrogen, lower alkyl, lower alkoxy, aryl or aryl-lower alkyl, R.sub.5 is lower alkyl, aryl, aryl-lower alkyl, unsaturated or saturated heterocyclyl-lower alkyl, or is also lower alkyloxycarbonyl-lower alkyl, and the salts thereof, to a process for the preparation of these compounds, to pharmaceutical compositions containing them, and to the use thereof as medicaments. ##STR1##
Claims10
A compound of formula I, ##STR9## wherein R.sub.1 is C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.5 alk-2-en-1-yl or C.sub.3 -C.sub.5 alk-2-yn-1-yl, R.sub.2 and R.sub.3 are each independently of the other hydrogen, identical C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkylidene groups, and R.sub.4 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.2 alkoxy, phenyl or phenyl-lower alkyl, R.sub.5 is C.sub.1 -C.sub.4 alkyl, phenyl, naphthyl, phenyl-lower alkyl, pyridyl-lower alkyl, thienyl-lower alkyl, pyrryl-lower alkyl, imidazolyl-lower alkyl, pyrrolidinyl-lower alkyl, tetrahydrofuranyl-lower alkyl or tetrahydropyranyl-lower alkyl or C.sub.1 -C.sub.4 alkoxycarbonyl-C.sub.1 -C.sub.4 alkyl, or a pharmaceutically acceptable salt thereof.
1-(3-Allyl-4-thiothiazolidin-2-ylidene)-4-allylthiosemicarbazone or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.