14.alpha.17.alpha.-(Propano-and 17.sup.2 propeno) -estratrienes
AssigneeSchering Corporation
InventorsJames R. Bull, Walter Elger, Karl-Heinrich Fritzemeier, Rolf Krattenmacher
Life of this patent
Estimating the term…
Abstract
14.alpha.,17.alpha.-(Propano-and 17.sup.2 -propeno)-estratrienes of general formula I ##STR1## in which R.sup.1 means a hydrogen atom, a methyl or an acyl group with 1-12 carbon atoms, R.sup.2 means a hydrogen atom or an acyl group with 1-12 carbon atoms and ##STR2## a C--C single or double bond. The new compounds of general formula I are estrogen effective just as ethinyl estradiol.
Claims6
A 14.alpha.,17.alpha.-(propano-or 17.sup.2 -propeno)-estratriene of formula I ##STR9## wherein R.sup.1 is H, methyl, or the acyl moiety of an aliphatic, cycloaliphatic, aliphatic-cycloaliphatic or aromatic C.sub.1-12 -monocarboxylic acid,
- R.sup.2 is H or the acyl moiety of an aliphatic, cycloaliphatic, aliphatic-cycloaliphatic or aromatic C.sub.1-12 -monocarboxylic acid,
- wherein the cycloaliphatic ring in R.sup.1 or R.sup.2 has 3-5 carbon atoms, and - - - is a C--C single or double bond.
Dependencies are inferred from the claim text.