Immobilization of biomolecules on a fluorocarbon surface with a poly(fluoroalkyl) sugar reagent

A process for immobilizing a biomolecule on a solid fluorocarbon polymer surface comprising the steps of:

• forming a conjugate by attaching to a biomolecule a poly(fluoroalkyl) sugar reagent, containing a sugar having multiple hydroxy groups to which are attached a plurality of fluoroalkyl anchor groups capable of adsorbing to a solid fluorocarbon polymer surface and a reactive group capable of attaching to a biomolecule, and adsorbing the conjugate on a solid fluorocarbon polymer surface to obtain said immobilized biomolecule, wherein the sugar reagent is selected from the group consisting of:
• ##STR10## wherein x=1-10;
• R is ##STR11## wherein m=1-5;
• n=3-20;
• and
• R' is:
• ##STR12## wherein x=1-10;
• R is CO(CH.sub.2).sub.m (CF.sub.2).sub.n CF.sub.3 wherein
• m=1-5;
• n=3-20;
• and
• R' is ##STR13## wherein:
• x=2-10;
• R is CO(CH.sub.2).sub.m (CF.sub.2).sub.n CF.sub.3 wherein
• m is 1-5;
• n is 3-20;
• and
• R' is:
• ##STR14##