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US 5,490,987 AGranted
Tableting of colestipol hydrochloride
AssigneeThe Upjohn Company
InventorsRobert W. Shen, Jeffrey E. Price
Life of this patent
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Abstract
The present invention provides a novel formulation of matter and a novel process for making it. In particular, the present invention provides unique and novel 1000 mg tablets of Colestipol hydrochloride having the advantageous properties of hardness and low friability and a novel process for making such tablets.
Claims17
A pharmaceutical tablet which comprises approximately 1000 mg of fine-milled colestipol hydrochloride, 10-200 mg of povidone, 1-50 mg of colloidal silicon dioxide and 1-30 mg of magnesium stearate, and which has the following physical characteristics:
- ______________________________________ Hardness:
- Greater than 40 SCU's Friability:
- 0-0.1%/15 minutes. ______________________________________
Dependencies are inferred from the claim text.