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US 5,489,585 AGranted
Alkoxylated phenyl and coumarin derivatives useful in the treatment of viral infections
AssigneeSchaper & Bruemmer GmbH & Co., KG
InventorsNorbert Beuscher, Helmut Ritter, Cornelia Bodinet
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Abstract
Alkoxylated phenyl and coumarin derivatives useful in the treatment of viral infections are disclosed. The compounds are particularly useful in the treatment of picornaviruses, and more particularly in the treatment of rhinoviruses.
Claims7
A method of treating a picornavirus infection in a subject infected with a picornavirus, comprising the step of administering an antiviral effective amount of a pharmaceutical composition comprising a coumarin derivative according to forumla I
- R.sup.1 -X-R.sup.2 (I)
- wherein
- X has from 2 to 12 carbon atoms and is an aliphatic group,
- R.sup.1 is represented by the formula Ia ##STR7## R.sup.2 is the same as R.sup.1 or is one of hydroxy, bromide, chloride, alkoxycarbonyl having from 1 to 6 carbon atoms, optionally-substituted amino and oxyphenyl of the formula Ic ##STR8## wherein R.sup.5 is alkyl or oxyalkyl, and
- m is an integer between 1 and 5, and a pharmaceutically acceptable excipient.
2 more elements
Dependencies are inferred from the claim text.