2-substituted 3-(4-amidinophenyl)propionic acid derivatives
AssigneeBASF SE
InventorsHelmut Mack, Thomas Pfeiffer, Hans W. Hoeffken, Hans-Joachim Boehm, Wilfried Hornberger
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Abstract
2-Substituted 3-(4-amidinophenyl)propionic acid derivatives of the formula ##STR1## in which A, Ar and B have the meanings stated in the description, and the preparation thereof are described. The compounds are suitable for controlling diseases.
Claims4
A 2-substituted 3-(4-amidinophenyl) propionic acid of the formula ##STR29## where A is ##STR30## or --OR.sup.3 in which R.sup.1 and R.sup.2, which can be identical or different, are each hydrogen, alkyl or alkenyl with up to 6 carbons, or R.sup.1 and R.sup.2 together with the nitrogen to which they are bonded are a 5-to 7-membered saturated ring which is unsubstituted or substituted by alkyl radicals with up to 4 carbons and can contain an oxygen atom, where the nitrogen and oxygen atoms are in the 1,2 or 1,4 positions, and where R.sup.3 is hydrogen, alkyl or alkenyl with up to 6 carbons,
- B is ##STR31## (where n is 1, 2, 3, 4 or 5) or ##STR32## Ar is phenyl or .alpha.- or .beta.-naphthyl which is unsubstituted or substituted by one or more halogen atoms, nitro groups, amino groups, C.sub.1-4 -mono- or bisalkylamino groups, hydroxyl groups, C.sub.1-4 -alkoxy groups, a methylenedioxy or ethylenedioxy radical, or Ar is pyridyl, quinolyl or isoquinolyl which is unsubstituted or substituted by one or more C.sub.1-4 -alkyl groups or C.sub.1-4 -alkoxy groups,
- and the salts thereof with physiologically tolerated acids.
Dependencies are inferred from the claim text.