Poultry mycoplasma antigen, gene thereof and recombinant vectors containing the gene as well as vaccines utilizing the same
AssigneesNippon Zeon Co., Ltd., Shionogi & Co., Ltd.
InventorsShuji Saito, Setsuko Ohkawa, Ayumi Fujisawa, Yoshikazu Iritani, Shigemi Aoyama
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Abstract
A highly effective vaccine for Mycoplasma gallisepticum infection utilizing a substantially pure protein capable of reacting with Mycoplasma gallisepticum immunized serum or Mycoplasma gallisepticum infected serum, having a molecular weight of about 40 kilodaltons encoded by DNA sequence derived from Mycoplasma gallisepticum and having a specific restriction enzyme map, or a protein functionally equivalent thereto.
Claims7
A substantially pure protein capable of reacting with Mycoplasma gallisepticum immunized serum or Mycoplasma gallisepticum infected serum, said protein having the sequence of SEQ ID NO:4, or said protein having a bacteria-derived enzyme fused to the N-terminus of SEQ ID NO:4.
An isolated DNA comprising the DNA sequence of SEQ ID NO:1.
An isolated DNA sequence comprising the sequence of nucleotides 202-1352 of SEQ ID NO:1 or a degenerate sequence thereof.
Dependencies are inferred from the claim text.