Biopolymers derived from hydrolyzable diacid fats
AssigneeYissum Research Development Company of the Hebrew University of Jerusalem
InventorsAbraham J. Domb, Raphael Nudelman
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Abstract
A monomeric diacid derivative includes at least two fatty acids coupled by hydrolytically or enzymatically degradable bond. In a biological environment, the bond degrades forming naturally occurring fatty acid products thereby allowing elimination.
Claims6
A polymer essentially consisting of repeating units of a monomeric diacid derivative comprising at least two fatty acids coupled by a hydrolytically or enzymatically degradable bond whereby said degradable bond in a biological environment degrades forming naturally occurring fatty acid products.
A drug release system comprising
- a pharmacologically effective amount of a drug and
- a polymer matrix essentially consisting of repeating units of a monomeric diacid derivative comprising at least two fatty acids coupled by a hydrolytically or enzymatically degradable bond whereby said degradable bond in a biological environment degrades forming naturally occurring fatty acid products
- wherein said drug is entrapped within said matrix and releasable upon degradation of said degradable bond.
A biocompatible, biodegradable, implantable material essentially consisting of repeating units of a monomeric diacid derivative comprising at least two fatty acids coupled by a hydrolytically or enzymatically degradable bond whereby said degradable bond in a biological environment degrades forming naturally occurring fatty acid products.
Dependencies are inferred from the claim text.