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US 5,480,935 AGranted
Cyanoacrylate adhesive compositions
AssigneeMedLogic Global Corporation
InventorsRichard J. Greff, Patrick J. Tighe, Michael M. Byram, Leonard V. Barley
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Abstract
Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably dioctyl phthalate), and SO.sub.2 as an artionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.
Claims9
An alkyl cyanoacrylate composition which comprises
- (a) from about 75 to 82 weight percent of an alkyl cyanoacrylate;
- (b) from about 50 to 500 parts per million of SO.sub.2, based on the entire weight of the composition, as a polymerization inhibitor;
- and
- (c) from about 18 percent to about 25 percent by weight of a biocompatible plasticizer which biocompatible plasticizer is a dialkyl phthalate wherein each alkyl group is independently from 1 to 10 carbon atoms
- wherein the alkyl cyanoacrylate, in monomeric form, is represented by formula I:
- ##STR5## where R is alkyl of 4 to 10 carbon atoms.
3 more elements
An alkyl cyanoacrylate composition which comprises
- (a) from about 75 to 80 weight percent of n-butyl cyanoacrylate;
- (b) about 200 parts per million of SO.sub.2, based on the entire weight of the composition, as a polymerization inhibitor;
- and
- (c) from about 20 percent to about 25 percent by weight of a dialkyl phthalate independently having from 1 to 10 carbon atoms in each alkyl group
- wherein the n-butyl cyanoacrylate, in monomeric form, is represented by formula I:
- ##STR6##
3 more elements
Dependencies are inferred from the claim text.