Injection device

For combination with

• a liquid-containing cartridge (11), wherein the cartridge has a plunger (23) displaceably located therein,
• an injection device for injecting a selected dose of a fluid from the cartridge into a subject, when the injection device is located proximally with respect to the subject,
• wherein the injection device comprises
• a housing (100) dimensioned to receive the cartridge (11);
• an adjustable-length tappet (80) which is axially displaceable relative to said housing (100) between a proximal end position and a distal end position thereof, including
• a dose-adjusting member (15) located within the housing (100) and having a thread (17), and
• a threaded spindle (19) guided in the thread (17) of said dose-adjusting member (15), said threaded spindle (19) being axially aligned with said plunger (23) in said cartridge (11) for acting on said plunger when the cartridge is positioned in the injection device;
• a spring means (53) having two ends, which ends are coupled, respectively, to said housing (100) and to said tappet (80) for axially biassing said dose-adjusting member (15) in a proximal direction;
• a guide member (67) located in the housing (100), axially slidably located on said threaded spindle (19), and secured against rotation relative to said threaded spindle (19);
• rotation-disabling means (92, 93) for disabling rotation of said guide member (67) relative to said housing (100) when said tappet (80) is in the proximal end position thereof while permitting rotation of the guide member (67) in the distal end position of said guide member (67);
• and
• retaining means (42, 118) for retaining said dose-adjusting member (15) in a rotational position, selected by a user when setting the dose to be injected by rotating said dose-adjusting member (15) in a setting direction (190), and
• wherein said retaining means (42, 118) is enabled when said tappet (80) is in its distal end position, and is disabled when said tappet (80) is in its proximal end position.