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US 5,478,837 AGranted
Use of quinacrine in preventing adhesion formation
AssigneeUniversity of Southern California
InventorsKathleen E. Rodgers, Gere S. Dizerega
Life of this patent
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Abstract
Compositions and methods for prevention of adhesion formation, whereby an effective amount of quinacrine as active agent is administered for a period of time sufficient to permit tissue repair. The active agent is preferably administered in conjunction with a delivery vehicle (e.g., microcapsules, microspheres, lipid-based systems, viscous instillates and absorbable mechanical barriers) useful for maintaining local concentrations of the compound at an effective level.
Claims15
A method for prevention in mammals of formation of adhesions between organ surfaces at a particular location, comprising:
- administering quinacrine as active agent to provide an effective local concentration at the location for a period of time sufficient to permit tissue repair.
Dependencies are inferred from the claim text.