Method of accelerating the proliferation of emdothelial cells with inhibition of no synthases
AssigneeRoussel Uclaf
InventorsChristian Bloy, Jean-Pierre Cazenave, Bernard Hercelin, Bernard Teisseire
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Abstract
A method of accelerating the proliferation of endothelial cells with inhibition of NO synthases in warm-blooded animals comprising administering to warm-blooded animals an amount of at least one compound selected from the group consisting of a .beta.-naphthoquinone of the formula ##STR1## wherein R is selected from the group consisting of --NH--CO--NH.sub.2, --NH--C0--CH.sub.3 and --0H and their non-toxic, pharmaceutically acceptable acid addition salts in an amount sufficient to accelerate the proliferation of endothelial cells.
Claims5
A method of accelerating the proliferation of endothelial cells with inhibition of NO synthases in warm-blooded animals comprising administering to warm-blooded animals an amount of at least one compound selected from the group consisting of a .beta.-naphthoquinone of the formula ##STR3## wherein R is selected from the group consisting of --NH--CO--NH.sub.2, --NH--CO--CH.sub.3 and --OH and their non-toxic, pharmaceutically acceptable acid addition salts in an amount sufficient to accelerate the proliferation of endothelial cells.
Dependencies are inferred from the claim text.