Liquid vitamin formulations containing vitamin D esters
AssigneeBristol-Myers Squibb Company
InventorMandar V. Shah
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Abstract
Liquid vitamin formulation containing an ester of antirachitic vitamin D esterified at the 3 carbon position such as vitamin D.sub.3 palmitate, greater than 252 mg/ml water and at least about 100 mg/ml polyhydroxylated solvent such as glycerine. The formulations have improved taste and improved storage stability.
Claims32
A liquid vitamin formulation at an acidic pH comprising per ml of composition an ester of antirachitic vitamin D, greater than 252 mg/ml water and at least about 100 mg/ml polyhydroxylated solvent, wherein said ester of antirachitic vitamin D is esterified at carbon 3.
A liquid vitamin formulation at a pH of between about 3.2 and about 5.6 comprising per ml of composition about 200 to about 1000 IU of a fatty acid ester of antirachitic vitamin D.sub.3 esterified at the 3 carbon, about 500 to about 950 mg/ml glycerin, and about 280 to about 550 mg/ml water.
Dependencies are inferred from the claim text.