TAN-1511, its derivatives, production and use thereof
AssigneeTakeda Chemical Industries, Ltd.
InventorsSeiichi Tanida, Tsuneaki Hida, Mitsuhiro Wakimasu
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Abstract
A compound of the formula: ##STR1## wherein each R.sup.1, R.sup.2 and R.sup.3 is an aliphatic acyl group, X is an amino acid sequence consisting of 1 to 5 amino acid residues which contain at least one acidic amino acid residue, n is an integer of 0 to 4, provided that when n is 0, X has glutamyl-glycyl at its N-terminal and when n is 1 or 2, the acidic amino acid residue is an acidic amino acid residue other than D-glutamyl, or a salt thereof has an activity of remarkably improving anhematopoiesis and is useful as an immuno-stimulating agent having a leukocyte-increasing activity.
Claims7
A compound of the formula:
- ##STR15## wherein each R.sup.1 R.sup.2 and r.sup.3 is an aliphatic acyl group, X is an amino acid sequence consisting of 1 to 4 amino acid residues, the N-terminal amino acid residue of said sequence being an acidic amino acid residue, the remaining amino acid residues of said sequence being selected from the group consisting of glycyl, alanyl, prolyl, leucyl and threonyl, and n is 3, or a salt thereof.
Dependencies are inferred from the claim text.