Use of relaxin in the treatment of bradycardia
AssigneeGenentech, Inc.
InventorsMichael Cronin, Phyllis L. Osheroff, G. Roger Thomas, David G. Ward
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Abstract
The invention concerns the use of relaxin or another compound capable of specific binding of a relaxin receptor in the heart in the cardiovascular therapy, and specifically in the treatment of acute and chronic heart failure or of a condition characterized by pathologically low heart rate. The invention further concerns the treatment of neurodegenerative diseases using relaxin or other compounds capable of selectively binding a relaxin receptor in the brain.
Claims11
A method of increasing heart rate comprising administering to a patient with sinus bradycardia caused by defective sinoatrial (SA) node function relaxin in an amount effective in increasing the heart rate to a normal level.
Dependencies are inferred from the claim text.