Process for producing acidic polycyclic ether antibiotic having anticoccidial and growth promant activity with Actinomadura
AssigneePfizer Inc.
InventorsJohn P. Dirlam, Walter P. Cullen, Hiroshi Maeda, Junsuke Tone
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Abstract
An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53764. This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.
Claims4
A process for the preparation of the compound of the formula ##STR2## wherein Me=methyl and Et=ethyl which comprises (a) culturing Actinomadura sp. ATCC 53764 under submerged aerobic conditions in an aqueous nutrient medium comprising an assimilable source of carbon and nitrogen until a recoverable amount of said compound is formed;
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- (b) recovering said compound.
Dependencies are inferred from the claim text.