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US 5,476,952 AGranted
Antitumor cyclopentnaphthoquinone and cyclopentanthraquinone derivatives
AssigneeSloan-Kettering Institute for Cancer Research
InventorsTsann-Long Su, Kyoichi A. Watanabe, Tiang-Chao Chou
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Abstract
The present invention provides compounds having the structure: ##STR1## or having the structure: ##STR2## The present invention also provides a pharmaceutical compostion containing the compounds, methods of synthesizing the compounds, as well as methods of inhibiting growth of tumor cells and of treating a subject having a disease characterized by the proliferation of tumor cells.
Claims3
A compound having the structure:
- ##STR59## wherein R' is H or a C1-C5 alkyl, hydroxyalkyl or haloalkyl group, wherein the halo atom is F, Cl, Br or I, and R" is H or a C1-C9 alkyl group.
A compound having the structure:
- ##STR60## wherein R' is H or a C1-C5 alkyl, hydroxyalkyl or haloalkyl group, wherein the halo atom is F, Cl, Br or I, and R" is H or a C1-C9 alkyl group.
Dependencies are inferred from the claim text.