Glycerin derivative and its pharmacological use

A glycerin derivative having the formula (I'), or a pharmacologically acceptable salt thereof:

• ##STR201## wherein A represents (1) a group of the formula:
• ##STR202## wherein n is an integer of 0 to 6, and R.sup.1, R.sup.2, and R.sup.3 each independently represent a hydrogen atom or an alkoxy group,
• (2) a group of the formula:
• ##STR203## wherein m is an integer of 0 to 6, or (3) a group of the formula:
• ##STR204## wherein p is an integer of 0 to 6;
• B is an alkyl group or an aryl group;
• and
• D represents a group of the formula:
• --Y--(CH.sub.2).sub.q --G
• wherein Y is selected from the group consisting of ##STR205## --O--(CH.sub.2).sub.r --NR.sup.7 --, ##STR206## wherein R.sup.4 is an aryl group or --CO--NR.sup.5 R.sup.6, R.sup.5 and R.sup.6 each independently represent a hydrogen atom or a lower alkyl, and R.sup.7 represents an acyl group, and r is an integer of 1 to 3;
• q is an integer of 0 to 3;
• and
• G is ##STR207## or --.sup.30 NR.sup.9 R.sup.10 R.sup.11 X.sup.-, wherein R.sup.9, R.sup.10, and R.sup.11 may be the same or different and each represents a lower alkyl group and X represents a pharmacologically allowable anion.