Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin
AssigneeJanssen Pharmaceutica NV
InventorGerard F. M. J. Cauwenbergh
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Abstract
A method of topically treating subjects suffering from acne, hyperkeratotic dermatoses and photo-aging of the skin, by administering to the skin of said subjects an effective amount of the antifungal compound ketoconazole and a retinoid is disclosed. Compositions comprising an inert carrier and as active ingredients the compound ketoconazole and a retinoid are described.
Claims12
A composition for treating acne, hyperkeratotic dermatoses, and photo-aging of the skin, consisting essentially of a skin acceptable carrier;
- from 5% to 25% by weight of a cyclodextrin or an ether derivative thereof;
- and as the sole pharmaceutically active ingredients, from 0.5% to 5% by weight of ketoconazole and from 0.005% to 0.5% by weight of a retinoid.
A method of topically treating acne, hyperkeratotic dermatoses or photo-aging of the skin in a patient suffering therefrom, which comprises administering to the affected site on the skin of the patient an effective amount of a composition consisting essentially of a skin acceptable carrier;
- from 5% to 25% by weight of a cyclodextrin or an ether derivative thereof;
- and as the sole pharmaceutically active ingredients, from 0.5% to 5% by weight of ketoconazole and from 0.005% to 0.5% by weight of a retinoid.
A composition for treating acne, hyperkeratotic dermatoses, and photo-aging of the skin, consisting essentially of a skin acceptable carrier;
- from 5% to 25% by weight of a cyclodextrin or an ether derivative thereof;
- and as the sole pharmaceutically active ingredients, from 0.5% to 5% by weight of ketoconazole and an effective amount of a retinoid.
Dependencies are inferred from the claim text.