Basophil granule proteins

An isolated and purified basophil protein (BGP) wherein the BGP has an N-terminal sequence described by a sequence selected from the group consisting of:

• Asp-Ile-Gly-Pro-Asp-Gln-His-Thr-Ser-Arg-Pro-Trp-Gly-Gln-Thr (SEQ. ID NO. 1);
• Asp-Val-Lys-Lys-Asp-Met-Glu-Val-Ser-Cys-Pro-Asp-Gly-Tyr-Thr
• (SEQ. ID NO. 2);
• Val-Met-X-Pro-Asp-Ala-Arg-Ser-X-Arg-Pro-Asp-Gly-X-Thr
• ( SEQ. ID NO. 3 );
• Ala-Ile-Tyr-X-Arg-Ile-Pro-X-X-Ile-Ala-Gly-Glu-Phe-Arg-Tyr-Gly-Thr-Val-Tyr-T yr-Gln-Gly-Ser-Leu (SEQ. ID NO. 4);
• Asp-Ile-Pro-Glu-Val-X-Val-X-Leu-Ala-Ala-Asp-Glu-Ser-Leu-Ala-Pro-Lys (SEQ. ID NO. 5);
• Tyr-Pro-Gln-Leu-Ala-Ile-Asn (SEQ. ID NO. 6);
• Ser-Ile-Gly-Phe-Val-Glu-Val-X-Leu-Val-Leu (SEQ. ID NO. 7);
• Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Thr-Cys-Ile (SEQ. ID NO. 8);
• Ala-Pro-Ala-Leu-Thr-Ile-Ser-Asn-Gln (SEQ. ID NO. 9);
• Asp-Ile-Gly-Pro-Asp-Gln-His-Thr-Ser-X.sub.1 -Pro-X.sub.2 -Gly-Gln-Thr-Arg-X-Pro-Gln-Leu-Thr-Gly-Gly-Glu-Ala-X-Val (SEQ. ID NO. 10);
• Arg-Asp-Val-Pro-Pro-Asp-X-Val-Val-Ser-X-Pro-Ser-Ser-Asp-Thr (SEQ. ID NO. 11);
• Gly-Pro-Pro-Thr-Phe-Asn-Lys-Ile-Thr-Pro-Asn-Asp-Ala-Asp-Phe (SEQ. ID NO. 14);
• Ala-Ile-Gln-Cys-Pro-X.sub.3 -Ser-Gln-Phe-X.sub.4 -X.sub.5 -Pro-X.sub.6 -Phe-Leu-Ala-Thr-Gly-Val-Met (SEQ. ID NO. 15 );
• Asp-Ile-Pro-Glu-Val-Cys-Phe-Asn (SEQ. ID NO. 16);
• Asp-Pro-Gly-Glu-Val-Lys-Ala-Leu-Pro-Met-Gln (SEQ. ID NO. 17);
• Lys-Pro-Gln-Met-Phe-Thr-Ile-X-Gln-Asn-X-Ala-Thr-Trp-Met (SEQ. ID NO. 18);
• Lys-Ile-Gly-Gly-Phe-Glu-Val-Thr-Asp-Val-Phe-Ala-Pro-Val-Met-Ala (SEQ. ID NO. 19);
• Ile-Leu-Gly-Val-Phe-X-Val-Glu-Gln-X-Phe-Ser-Phe-X-Leu (SEQ. ID NO. 20);
• Asp-Pro-Pro-Thr-Phe-Asn-Lys-Ile-Thr-Pro-Asn-Leu-Leu-Glu-Phe-Ala-Asp-Gly-Leu -Tyr-Lys-Gln-Glu (SEQ. ID NO. 21);
• and
• Ser-Glu-Leu-Thr-Lys-Met-Asn-Gln-Arg-Ser-Phe (SEQ. ID NO. 22);
• where each X, X.sub.1, X.sub.2, X.sub.3, X.sub.4, X.sub.5 and X.sub.6 independently represents a variable amino acid residue.