Gonococcal anti-idiotypic antibodies and methods and compositions using them
OwnerPeter A. Rice, Sunita Gulati +1inventors
InventorsPeter A. Rice, Sunita Gulati, Daniel P. McQuillen
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Abstract
The present invention relates to anti-idiotypic antibodies directed against Neisseria gonorrhoeae. This invention also relates to methods and compositions using such anti-idiotypic antibodies for the prophylaxis, treatment and diagnosis of gonorrheal infections.
Claims6
An anti-idiotypic monoclonal antibody, or binding fragment thereof, characterized by an antigen combining site which immunospecifically binds to the idiotype of a second antibody which binds to an oligosaccharide epitope of N. gonorrhoeae, which oligosaccharide epitope is not present in human blood group antigens, wherein the oligosaccharide epitope specifically binds to monoclonal antibody 2C7 produced by hybridoma HB-11859.
An anti-idiotypic monoclonal antibody, or binding fragment thereof, produced by a hybridoma cell line having the characteristics of HB 11311 as deposited with the ATCC.
Dependencies are inferred from the claim text.