Retention time stability in a gas chromatographic apparatus
AssigneeHewlett-Packard Company
InventorsRobert Henderson, Edwin Wikfors
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AssigneeHewlett-Packard Company
InventorsRobert Henderson, Edwin Wikfors
Estimating the term…
The effect of barometric pressure variation on the retention time stability of a chromatographic analytical system is compensated by active control of the amount of fluid flow by way of a fluid flow controller, preferably in the form of an electronic pressure control system. Control signals are derived by: receiving data representative of a desired operating condition parameter, such as column inlet pressure; sensing actual operating condition parameters such as inlet pressure p.sub.i and barometric pressure p.sub.atm ; determining a desired average linear velocity of the fluid flow according to the desired operating system parameter; determining an actual average linear velocity of the fluid flow according to the sensed plurality of actual operating condition parameters; and controlling, as a function of a predetermined relationship of the desired average linear velocity to the actual average linear velocity, the amount of fluid flow to cause the actual average linear velocity to substantially equal the desired average linear velocity.
A method for performing a chromatographic analysis of a fluid in a separation column having an outlet subject to a barometric pressure p.sub.atm, comprising the steps of:
Apparatus for performing a chromatographic analysis of a fluid in a separation column having an outlet subject to a barometric pressure p.sub.atm, comprising:
Dependencies are inferred from the claim text.