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US 5,475,132 AGranted
Antifungal agents based on amides containing a phenyl group
AssigneeRhone-Poulenc Agrochimie
InventorsRegis Pepin, Christian Schmitz, Guy-Bernard Lacroix, Philippe Dellis, Christine Veyrat
Life of this patent
Estimating the term…
Abstract
R.sub.3, R.sub.4 and R.sub.5, each represents a hydrogen or halogen atom (at least one of R.sub.3, R.sub.4 and R.sub.5 being other than hydrogen or halogen); optionally substituted amino; optionally halogenated or hydroxylated alkyl, alkoxy, alkylalkoxy or alkylthio; or R.sub.3 and R.sub.4 (in the 3- and 4-positions) can together form a single divalent radical with 3 or 4 members containing 1 or 2 non-adjacent oxygen atoms; are useful as agricultural fungicides.
Claims6
A compound having the formula
- wherein:
- Z.sub.2 is OW.sub.2 wherein W.sub.2 is a hydrogen atom, a lower alkyl radical or an alkali metal or alkaline earth metal atom;
- R.sub.23 is methoxy and R.sub.24 is methoxy, or R.sub.23 and R.sub.24 together form a methylenedioxy or ethylenedioxy group, the carbon atoms of which are optionally substituted by lower alkyl or halogen:
- R.sub.25 represents:
- a hydrogen or halogen atom;
- an amino group which is optionally substituted by one or two lower alkyl groups;
- a lower alkyl, lower alkoxy, (lower)alkoxy-(lower)alkyl or lower alkylthio group, each of which is optionally halogenated or hydroxylated;
- R.sub.26 and R.sub.27, which are identical or different, each represent:
- hydrogen or halogen, at least one of R.sub.26 and R.sub.27 being other than hydrogen;
- cyano, nitro, thiocyanato, hydroxyl or carboxyl;
- alkyl, cycloalkyl, alkenyl, alkynyl, alkyl-S(O).sub.n (wherein n is 0, 1 or 2), alkoxy, cycloalkoxy, alkenyloxy or alkynyloxy, each of which has up to 8 carbon atoms and is optionally substituted by one or more halogen atoms;
- (lower)alkoxy-carbonyl, CO--NR'R", NR'R", N(R')--OC--R", O--CO--R' or O--CO--NR'R";
- or
- phenyl, naphthyl, phenyl-S(O).sub.n (wherein n is 0, 1 or 2), phenoxy, phenyl-(lower)alkyl, phenyl-(lower)alkyl-S(O).sub.n (wherein n is 0, 1 or 2), phenyl-(lower)alkoxy or thienyl, the phenyl or thienyl rings being unsubstituted or substituted by:
- halogen;
- nitro, cyano, carboxyl, hydroxyl, mercapto, thiocyanato, (lower)alkoxy-carbonyl, --CO--NR'R", --NR'R", --N(R')--CO--R", --O--CO--R' or --O--CO--NR'R";
- or
- lower alkyl, lower alkoxy, (lower)alkyl-S(O).sub.n (wherein n is 0, 1 or 2), cycloalkyl having 3 to 7 carbon atoms, phenyl, phenoxy, phenyl-S(O).sub.n (wherein n is 0, 1 or 2), phenylalkyl, phenylalkoxy or phenylalkyl-S(O).sub.n (wherein n is 0, 1 or 2), which is optionally halogenated and has 1 to 4 carbon atoms in the alkyl portion;
- R' and R", which are identical or different, each represent hydrogen;
- lower alkyl;
- cycloalkyl having 3 to 7 carbon atoms;
- optionally halogenated phenyl;
- optionally halogenated phenyl-(lower)alkyl;
- alkenyl or alkynyl having 3 to 7 carbon atoms;
- or alkoxyalkyl having 3 to 8 carbon atoms;
- and
- R.sub.28 and R.sub.29, which are identical or different, each represent hydrogen or halogen;
- hydroxyl;
- lower alkyl;
- lower alkoxy;
- (lower)alkoxy-(lower)alkyl;
- or (lower)alkoxycarbonyl;
- with the proviso that when R.sub.28 represents hydroxyl and R.sub.26 represents methyl, then W.sub.2 is other than hydrogen.
30 more elements
Dependencies are inferred from the claim text.