N-substituted azabicycloheptane derivatives

An N-substituted 3-azabicyclo[3.2.0]heptane derivative of the formula I ##STR16## where R.sup.1 is phenyl, pyridyl, thienyl or pyrrole, each of which is unsubstituted or mono- or disubstituted by halogen, C.sub.1 -C.sub.4 -alkyl, trifluoromethyl, hydroxyl, C.sub.1 -C.sub.4 -alkoxy, amino, monomethylamino, dimethylamino, cyano or nitro,

• R.sup.2 is hydrogen or phenyl which is unsubstituted or substituted by halogen, methoxy, hydroxyl or amino,
• n is 0, 1, 2, 3 or 4,
• R.sup.3 is hydrogen, hydroxyl, C.sub.1 -C.sub.4 allkyl or C.sub.1 -C.sub.4 -alkoxy, or together with the adjacent carbon atom is C.dbd.O or C.dbd.S,
• X and Y are each C, CH, CH.sub.2, NH or C.sub.1 -C.sub.4 alkyl-N or N,
• Z is a direct linkage, CO, CS or CH or CH.sub.2 in which one hydrogen can be replaced by hydroxyl, amino, C.sub.1 -C.sub.1 -alkoxy or halogen, and
• A is hydrogen, hydroxyl, amino, mercapto, C.sub.1 -C.sub.4 -alkyl-amino, di-C.sub.1 -C.sub.4 -alkylamino, C.sub.1 -C.sub.1 -alkylthio or C.sub.1 -C.sub.4 -alkoxy, or together with the adjacent carbon atom is C.dbd.O, or
• A is C.sub.3 -C.sub.4 -alkylene which is attached to Y and which can contain one or two non-cumulative double bonds and in which one CH or CH.sub.2 can be replaced by N, S, NH or N--CH.sub.3, and where the ring can be either mono-substituted by fluorine, chlorine, methyl, methoxy, nitro or amino or, in the case of a benzene ring, mono-, di- or trisubstituted by fluorine, chlorine, methyl, trifluoromethyl, nitro, hydroxyl, methoxy, amino, monomethylamino or dimethylamino, and in which the ring on the right in formula I can have C.sub.1 -C.sub.4 -alkyl, allyl or benzyl attached to N-1 and can contain 1-3 non-cumulative double bonds, and the salts thereof with physiologically tolerated acids.