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US 5,474,918 AGranted
Process for the production of L-threonine and L-isoleucine by fermentation of Escherichia coli
AssigneeKyowa Kakko Kogyo Co., Ltd.
InventorsKuniki Kino, Kazuyuki Okamoto, Yasuya Takeda, Yoshiyuki Kuratsu
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Abstract
A process for the production of L-threonine by fermentation of Escherichia coli FERM BP-3756 or Escherichia coli FERM BP-4072 and a process for the production of L-isoleucine by the fermentation of Escherichia coli FERM BP-3757 is disclosed. The strains are resistant to purine analogues such as 6-dimethylaminopurine or 6-methylaminopurine.
Claims2
A process for the production of L-threonine by fermentation which comprises:
- culturing in a nutrient medium a microorganism which is selected from the group consisting of Escherichia coli FERM BP-3756 and Escherichia coli FERM BP-4072 under conditions sufficient for the production of L-threonine, and recovering L-threonine therefrom.
A process for the production of L-isoleucine by fermentation, which comprises:
- culturing in a nutrient medium Escherichia coli FERM BP-3757 under conditions sufficient for the production of L-isoleucine, and recovering L-isoleucine therefrom.
Dependencies are inferred from the claim text.