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US 5,474,784 AGranted
Dispensing device
AssigneeBritish Technology Group Limited
InventorsHoward N. E. Stevens, Abdul Rashid, Massoud Bakhshaee
Life of this patent
Estimating the term…
Abstract
A controlled release device useful especially as an oral dosage form for man comprises a water impermeable capsule having at least one orifice which orifice is closed by a water swellable or water dispersable plug. Preferably the capsule is a cylinder formed e.g. of polyethylene closed at one end. The open end is closed by a tablet formed e.g. by direct compression of a pharmaceutical excipient such as lactose.
Claims19
A capsule suitable for human oral administration, comprising:
- (a) a hollow body having a water-impermeable external surface and an orifice through which the contents of the hollow body are to be released as a pulse in the human body;
- and
- (b) a plug consisting essentially of a water-soluble or water-dispersible material closing said orifice, wherein said plug provides a pulsed release of the capsule contents after a controlled delay between introduction of the capsule into an aqueous environment and exposure of the capsule contents to said environment, said plug being composed of a compressed pharmaceutically acceptable material.
Dependencies are inferred from the claim text.