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US 5,474,779 AGranted
Compositions for aiding in the regeneration of tissue with a prolonged immunomodulating effect
OwnerNataliya Bufius, Nataliya Galatenkoinventors
Life of this patent
Estimating the term…
Abstract
A composition including levamisol is applied to a tumor removal site to activate macrophages, promote tumor cell reversion and accelerate regenerative tissue in the cavity. The composition forms a porous sponge-like material which fills the cavity and provides a supporting structure for regeneration of tissue, growth reversion of the tumor and activation of macrophage elements.
Claims9
A composition for application to a tumor removal site which is placed into the cavity formed by the tumor removal, comprising:
- a biodegradable polyurethane base which is capable of polymerizing at physiological temperature to form a sponge-like structure;
- a therapeutically effective amount of a macrophage activating additive;
- and
- 2,4,6-tris(dimethylaminomethyl)phenol as an accelerator.
1 more element
A composition applicable in the medical field, comprising:
- a non-toxic, liquid biodegradable polyurethane base which is capable of polymerizing at physiological temperature to produce a non-toxic cellular foam structure and which permits and encourages connective tissue growth;
- approximately 6 to 8 wt. % levamisole;
- and
- approximately 4 wt. % of 2,4,6-tris(dimethylaminomethyl)phenol as an accelerator which reacts with the base and causes the foam structure to be produced.
1 more element
Dependencies are inferred from the claim text.