Granules of .alpha.-L-aspartyl-L-phenylalanine methyl ester

Granules of alpha-L-aspartyl-L-phenylalanine methyl ester containing IB crystals of alpha-L-aspartyl-L-phenylalanine methyl ester, wherein said granules are prepared by a process comprising the steps of:

• (i) crystallizing alpha-L-aspartyl-L-phenylalanine methyl ester by stirring crystallization to obtain crystals (a) of alpha-L-aspartyl-L-phenylalanine methyl ester or by pseudo-solid phase cooling crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester to obtain crystals (b) of alpha-L-aspartyl-L-phenylalanine methyl ester, and
• (ii) sieving said crystals (a) or said crystals (b) with sieves having 100 micron and 1400 micron holes therein, respectively, to obtain said sieved granules.

A package consisting essentially of a packaging material and granules of alpha-L-aspartyl-L-phenylalanine methyl ester, wherein said granules contain IB crystals of alpha-L-aspartyl-L-phenylalanine methyl ester and consist essentially of grain sizes within the range of 100-1400 microns.

A package consisting essentially of a packaging material and sieved granules of alpha-L-aspartyl-L-phenylalanine methyl ester containing IB crystals of alpha-L-aspartyl-L-phenylalanine methyl ester, wherein said granules are prepared by a process comprising the steps of:

• (i) crystallizing alpha-L-aspartyl-L-phenylalanine methyl ester by stirring crystallization to obtain crystals (a) of alpha-L-aspartyl-L-phenylalanine methyl ester or by pseudo-solid phase cooling crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester to obtain crystals (b) of alpha-L-aspartyl-L-phenylalanine methyl ester, and
• (ii) sieving said crystals (a) or said crystals (b) with sieves having 100 micron and 1400 micron holes therein, respectively, to obtain said sieved granules.