Method for the treatment of uterine fibroid desease
AssigneeEli Lilly and Company
InventorsHenry U. Bryant, Jeffrey A. Dodge
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AssigneeEli Lilly and Company
InventorsHenry U. Bryant, Jeffrey A. Dodge
Estimating the term…
The present invention provides novel methods of lowering serum cholesterol and inhibiting smoother muscle cell proliferation, particularly restenosis, in humans, and inhibiting uterine fibroid disease and endometriosis in women comprising administering to a human/woman in need of treatment an effective amount of a compound of formula I ##STR1## wherein R is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halo, or trifluoromethyl; R.sup.1 and R.sup.2 each are the same or different C.sub.1 -C.sub.6 alkyl group; n is an integer from 2 to 6; and R.sup.3 and R.sup.4 each are independently C.sub.1 -C.sub.4 alkyl, or combine to form a substituent selected from the group consisting of pyrrolidino, morpholino, piperidino, piperazino, 4-(C.sub.1 -C.sub.6 alkyl)piperazino, and 4-phenyl-piperazino; or a pharmaceutically acceptable salt thereof.
A method for inhibiting uterine fibroid disease comprising administering to a woman in need of such treatment an effective amount of a compound of formula I ##STR4## wherein R is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halo, or trifluoromethyl;
Dependencies are inferred from the claim text.