Chemical compounds and process
AssigneeResearch Institute for Medicine and Chemistry Inc.
InventorsRobert H. Hesse, Ezio Rizzardo, Derek H. R. Barton
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Abstract
The invention provides novel compositions for use in pharmaceutical and veterinary medicine which contain 1.alpha.-hydroxy vitamin D compounds. Particular compositions are described which contain steroids which induce or assist in combatting osteoporosis together with 1.alpha.-hydroxy vitamin D.sub.3 or 1.alpha.,25-dihydroxy vitamin D.sub.3. Methods of treatment of diseases are also provided including many which are resistant to vitamin D.sub.3, in particular bone diseases.
Claims13
A method of treatment or prevention of vitamin D resistant diseases comprising administering to a human subject a pharmaceutical composition in unit dosage form containing from 0.2 to 5.0 .mu.g of 1.alpha.-hydroxy vitamin D.sub.3 and not exceeding 5.0 .mu.g per day.
Dependencies are inferred from the claim text.