Loading patent…
AssigneeSynaptic Pharmaceutical Corporation
InventorsChristophe Gerald, Paul R. Hartig, Theresa A. Branchek, Richard L. Weinshank
Estimating the term…
This invention provides an isolated nucleic acid molecule encoding a mammalian 5-HT.sub.4A receptor and an isolated nucleic acid molecule encoding a human 5-HT.sub.4A receptor, an isolated protein which is a mammalian 5-HT.sub.4A receptor, an isolated protein which is a human 5-HT.sub.4A receptor, vectors comprising an isolated nucleic acid molecule encoding a mammalian 5-HT.sub.4A receptor, vectors comprising an isolated nucleic acid molecule encoding a human 5-HT.sub.4A receptor, mammalian cells comprising such vectors, antibodies directed to the 5-HT.sub.4A receptor, nucleic acid probes useful for detecting nucleic acid encoding a mammalian or human 5-HT.sub.4A receptor, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a mammalian or human 5-HT.sub.4A receptor, pharmaceutical compounds related to the human 5-HT.sub.4A receptor, and nonhuman transgenic animals which express DNA encoding a normal or a mutant mammalian or human 5-HT.sub.4A receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatments for alleviating abnormalities associated with a human 5-HT.sub.4A receptor.
An isolated nucleic acid molecule encoding a mammalian 5-HT4A receptor having the amino acid sequence shown in FIG. 1 (Seq. I.D. No. 2).
An isolated nucleic acid molecule encoding a mammalian 5-HT4A receptor having the amino acid sequence shown in FIG. 2 (Seq. I.D. No. 4).
Dependencies are inferred from the claim text.