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US 5,472,705 AGranted
Pharmaceutical composition containing esters of .omega.-3 polyunsaturated acids and their use in the topical treatment of morbid affections
AssigneeProspa B.V.
InventorsTiberio Bruzzese, Giovanni Mozzi, Remo Ruggeri
Life of this patent
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Abstract
New pharmaceutical compositions for topical use containing esters of .omega.-3 polyunsaturated acids having a high concentration have been obtained. Such formulations have been added with phenolic antioxidants and with adjuvants. The present formulations have been found clinically useful in the treatment of morbid affections, in particular in the treatment of psoriasis, phlebitis and the correlated pathologies.
Claims14
A topical composition for treating morbid affections, comprising:
- (a) 25% to 40% by weight of at least one C.sub.1-3 alkyl ester of a .omega.-3 polyunsaturated fatty acid selected from the group consisting of a C.sub.1-3 alkyl ester of cis-5, 8, 11, 14, 17-eicosapentaenoic acid and a C.sub.1-3 alkyl ester of cis-4, 7, 10, 13, 16, 19-docosahexaenoic acid, wherein said at least one C.sub.1-3 alkyl ester of a .omega.-3 polyunsaturated fatty acid has a titer of at least 80%;
- (b) 1% to 4% by weight with respect to said at least one C.sub.1-3 alkyl ester (a) of at least one phenolic antioxidant;
- and
- (c) 5% to 15% by weight with respect to said at least one C.sub.1-3 alkyl ester (a) of triethylcitrate.
1 more element
Dependencies are inferred from the claim text.