Nanoparticulate diagnostic mixed carbamic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging
AssigneeEastman Kodak Company
InventorCarl R. Illig
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AssigneeEastman Kodak Company
InventorCarl R. Illig
Estimating the term…
This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen, and/or lymph system of a mammal comprising administering a contrast effective amount of a mixed carbamic anhydride as a contrast agent having the structure ##STR1## X is H, NR.sup.1 R.sup.2 or CONR.sup.1 R.sup.3, R.sup.1 is H or alkyl R.sup.2 is COR.sup.3 R.sup.3 is H, alkyl or aryl Y is NR.sup.1 R.sup.2 or CONR.sup.1 R.sup.3 and N is NR.sup.1 R.sup.4 and R.sup.4 is H, alkyl, aryl or CH(R.sup.5)CO.sub.2 R.sup.1. This invention further relates to novel mixed carbamic anhydride contrast agents having the above structure to x-ray contrast compositions comprising such agents, and to methods of x-ray diagnostic imaging utilizing such agents.
A method of medical x-ray diagnostic imaging the blood pool, liver, spleen, or lymph system of a mammal comprising administering to the mammal a contrast effective amount of a mixed carbamic anhydride contrast agent having the structure ##STR10## wherein X is H, NR.sup.1 R.sup.2 or CONR.sup.1 R.sup.3,
A compound having the structure ##STR11## X is H, NR.sup.1 R.sup.2 or CONR.sup.1 R.sup.3, R.sup.1 is H or alkyl
Dependencies are inferred from the claim text.