Method for treating transition zone material
AssigneePall Corporation
InventorsVlado I. Matkovich, Thomas J. Bormann, Thomas C. Gsell, Frank R. Pascale, Keith S. Morris
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Abstract
Methods and devices for treating transition zone material are disclosed. Transition zone material is processed to form a supernatant layer which includes platelets and a sediment layer which includes red blood cells, and the supernatant layer is separated from the sediment layer by passing the supernatant layer through a porous medium. Once the supernatant layer has been separated from the sediment layer, gas may be separated from the supernatant layer.
Claims15
A method for processing a biological fluid comprising:
- processing a transition zone material of a biological fluid to form a supernatant layer which includes platelets and a sediment layer which includes red blood cells;
- separating the supernatant layer from the sediment layer by passing the supernatant layer through a porous medium into a downstream container;
- and,
- separating gas from the supernatant layer in the downstream container by passing gas and a portion of the supernatant layer from the downstream container into a gas collection and displacement loop.
A method for processing a transition zone material comprising:
- pooling the transition zone material;
- processing the pooled transition zone material to form a supernatant layer which includes platelets and a sediment layer which includes red blood cells;
- and
- separating the supernatant layer from the sediment layer by passing the supernatant layer through a porous medium into a downstream container;
- and,
- separating gas from the supernatant layer in the downstream container by passing gas and a portion of the supernatant layer from the downstream container into a gas collection and displacement loop.
A method for processing a biological fluid comprising:
- passing a biological fluid through a leukocyte depletion filter assembly and into a container downstream of the filter assembly, thereby displacing gas into the downstream container;
- passing gas and a portion of the biological fluid from the container into a gas collection and displacement loop.
A method for processing a biological fluid comprising:
- passing a biological fluid through a leukocyte depletion filter assembly and into a container downstream of the filter assembly;
- separating gas displaced by the biological fluid into the container by passing the gas from the container into a gas collection and displacement loop;
- and,
- passing a sample of the biological fluid from the container into the gas collection and displacement loop.
A method for isolating leukocyte-depleted biological fluid from leukocyte-containing biological fluid in a closed sterile system comprising:
- passing a leukocyte-containing biological fluid through a leukocyte depletion filter assembly and into a container downstream of the filter assembly;
- and,
- passing gas and a portion of the leukocyte-depleted biological fluid from the downstream container into a gas collection and displacement loop including a liquid barrier medium that prevents the passage of leukocyte-containing biological fluid therethrough.
Dependencies are inferred from the claim text.