Back to results
US 5,470,983 AGranted
Preparation of omeprazole and lansoprazole, and intermediates useful therein
AssigneeTorcan Chemical Ltd.
InventorsClarke Slemon, Bob Macel
Life of this patent
Estimating the term…
Abstract
Omeprazole and lansoprazole, which are chemically pyridine-benzimidazole sulfinyl compounds, are produced from the corresponding acetamide-sulfide compounds by a process of oxidation to form the amide sulfinyl compound, followed by alkaline hydrolysis to the sulfinyl carboxylate or salt, and decarboxylation.
Claims3
The sulfoxide-carboxylate compound of the formula:
- ##STR14## in which either (a) R and R.sub.1 are each methyl and R.sub.2 is methoxy;
- or (b) R is 1,1,1-trifuloromethyl and R.sub.1 and R.sub.2 are both hydrogen;
- x is an alkali metal, y is hydrogen or an alkali metal, or x and y together represent a divalent alkaline earth metal.
Dependencies are inferred from the claim text.