Antisera against a PEB1 antigen from Campylobacter jejuni
AssigneeEnteric Research Laboratories, Inc.
InventorsMartin J. Blaser, Richard T. Ellison, III, Zhi H. Pei
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Abstract
An antigenic composition includes antigens obtainable from Campylobacter jejuni and may be used as a vaccine to induce protective antibodies against both Campylobacter coli and Campylobacter jejuni. The antigenic composition, and antisera specific to the antigens can be used to detect Campylobacter coli or Campylobacter jejuni infection. Diagnostic detection kits include the novel antigenic composition or antisera thereto.
Claims1
Antisera raised against a purified PEB1 antigen which is obtained from Campylobacter jejuni and has an apparent molecular weight of 28 kDa as measured on sodium dodecyl sulfate polyacrylamide gel under reducing conditions, a molecular weight of 28.9.+-.1.0 kDa as measured by gel filtration chromatography under native conditions, and an isoelectric point of 8.5.
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