Imidazoles and their salts having antagonistic activity to angiotesin II recetors

A compound selected from the group consisting of a compound of the formula ##STR156## wherein R.sub.b is n-butyl or butenyl, one of Z.sub.1, Z.sub.2 and Z.sub.3 is sulfur and the other two are .dbd.CH--, R.sub.1b and R.sub.2b are individually selected from the group consisting of hydrogen;

• halogen;
• --OH, --SH;
• alkoxy, alkyl and alkylthio of 1 to 6 carbon atoms, alkenyl and alkynyl of 2 to 6 carbon atoms, carbocyclic aryl, carbocyclic aralkyl and carbocyclic aralkenyl with up to 6 alkyl and alkenyl carbon atoms, all the alkyl, alkenyl, alkynyl, alkylthio, aryl, aralkyl and aralkenyl unsubstituted or substituted with at least one member of the group consisting of halogen, --OH, --SH, alkoxy and alkylthio of 1 to 4 carbon atoms, acyl and acyloxy;
• carboxy and carboxy esterified with alkyl of 1 to 4 carbon atoms, Y.sub.1b is phenyl, B.sub.b is a single bond or ##STR157## and when B.sub.b is a single bond or ##STR158## Y.sub.2b is phenyl unsubstituted or substituted with carboxy, esterified carboxy tetrazolyl, tetrazolyl-methyl or tetrazolyl-carbamoyl, --SO.sub.2 --X.sub.b --R.sub.14b, X.sub.b is selected from the group consisting of a single bond, --NH--, --CO-- and ##STR159## and R.sub.14b is selected from the group consisting of methyl, ethyl, vinyl, allyl, pyridylmethyl, pyridylethyl, pyridyl, phenyl and benzyl and when B.sub.b is a single bond, Y.sub.2b is cyano or free carboxy, salified or carboxy esterified with alkyl of 1 to 4 carbon atoms with the proviso that at least one of R.sub.1b and R.sub.2b is --OH and their non-toxic pharmaceutically acceptable salts with acid and base.