Method for diagnosing kawasaki syndrome
AssigneesNational Jewish Center for Immunology and Respiratory Medicine, New England Medical Center Hospital, Inc., University of Minnesota, Regents of the University of Minnesota
InventorsDonald Leung, Patrick Schlievert, Cody Meissner, David Fulton
Life of this patent
Estimating the term…
Abstract
The invention relates to various methodologies for diagnosing Kawasaki syndrome. Various bacteria, including TSST-1 producing Staphylococcus aureus, and SPEB and SPEC producing streptococcus have been found to be indicative of the pathological condition. Also described is a Kawasaki syndrome implicated isolate of S. aureus, and therapeutic methodologies for preventing treating the condition.
Claims6
Method for screening for possibility of Kawasaki Syndrome in a subject, comprising assaying a sample taken from a subject suspected of being afflicted with Kawasaki Syndrome who exhibits primary clinical manifestations of Kawasaki Syndrome with an antibody which specifically binds to toxic shock syndrome toxin-1 (TSST-1) and determining binding between TSST-1 and said antibody as an indication of possibility of Kawasaki Syndrome in said subject.
Method for screening for possibility of Kawasaki Syndrome in a subject, comprising assaying a sample taken from said subject for presence of Staphylococcus aureus which is white in appearance and produces toxic shock syndrome toxin-1 (TSST-1) as an indication of possible Kawasaki Syndrome in said subject.
Dependencies are inferred from the claim text.