Use of orally absorbable motilin preparations to enhance motility of digestive tract
AssigneeSanwa Kagaku Kenkyusho Co., Ltd.
InventorsKiichi Sawai, Masayasu Kurono, Takahiko Mitani, Makoto Sato, Hiroyuki Oowaki, Bunkichi Kato, Haruo Takahashi
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Abstract
A readily absorbable type of motilin preparation containing a motilin-like active substance and a surface active agent is provided, in which the motilin-like active substance is mainly L-leucine-13-motilin-homoserine, and the surface active agent is selected from the group consisting of a bile salt, saponin and a polyethylene glycol higher-alcohol ether for nasal administration purposes and is a peptide lytic enzyme inhibitor for oral administration purposes.
Claims2
A method of enhancing motility of the digestive tract in a mammal which comprises orally or nasally administering to a mammal in need of such enhancement a pharmaceutical preparation comprising a peptide exhibiting motilin activity, a peptide lyric enzyme inhibitor and a surface active agent.
Dependencies are inferred from the claim text.