Heteromorphic sponges containing active agents
AssigneeJohnson & Johnson Medical, Inc.
InventorsArthur L. Rosenthal, Nicholas D. Light, Carla A. Haynes
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Abstract
The invention provides wound dressing and/or implant materials comprising a matrix structure of sponge, at least one substructure and at least one pharmacologically active agent, wherein both the matrix structure and the substructure are formed from bioabsorbable biopolymer materials. The substructure may, for example, comprise biopolymer films, flakes, fibres or microspheres embedded in the matrix structure of sponge. The pharmacologically active agent may comprise antiseptics, antibiotics, analgesics. One or more such active agents may be incorporated separately into the matrix and/or the substructure so as to achieve controlled or phasic release of the active agents into the wound.
Claims6
A bioabsorable heteromorphic sponge comprising:
- a matrix structure of sponge, at least one macroscopic substructure and at least one pharmacologically active agent, wherein the matrix structure and the said at least one macroscopic substructure are formed of bioabsorable biopolymer materials and said at least one substructure is selected from the group consisting of milled freeze-dried sponges, powders, films, flaked or broken films, aggregates, microspheres, fibres, fibre bundles, and mixtures thereof.
Dependencies are inferred from the claim text.