Insecticidally effective peptides
AssigneesFMC Corporation, NPS Pharmaceuticals, Inc.
InventorsKaren J. Krapcho, J. R. Hunter Jackson, Bradford C. VanWagenen, Robert M. Kral, Jr.
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Abstract
The invention provides insecticidally effective peptides isolatable from Diguetia spider venom, methods for preparing and using insecticides, and DNA encoding such insecticidally effective peptides.
Claims8
A substantially purified, insecticidally effective peptide isolatable from Diguetia spider venom or an agriculturally or horticulturally acceptable salt thereof comprising the amino acid sequence defined in SEQ ID NO:1.
A substantially purified, insecticidally effective peptide isolatable from Diguetia spider venom or an agriculturally or horticulturally acceptable salt thereof comprising the amino acid sequence defined in SEQ ID NO:3.
A substantially purified, insecticidally effective peptide isolatable from Diguetia spider venom or an agriculturally or horticulturally acceptable salt thereof comprising the amino acid sequence defined in SEQ ID NO:5.
A method for producing an insecticidally effective peptide comprising:
- (a) culturing recombinant Spodoptera frugiperda host cells having a recombinant baculovirus expression vector transformed or transfected in said host cells and having a DNA sequence encoding the peptide defined in SEQ ID NO:1, wherein said vector is capable of effecting the expression of said coding sequence in transformed cells;
- and
- (b) recovering said insecticidally effective peptide from the recombinant host cell culture.
A method of controlling insects of the order Lepidoptera comprising contacting said insects with an effective amount of a peptide comprising the amino acid sequence defined in SEQ ID NO:1.
A method of controlling insects of the order Lepidoptera comprising contacting said insects with an effective amount of a peptide comprising the amino acid sequence defined in SEQ ID NO:3.
A method of controlling insects of the order Lepidoptera comprising contacting said insects with an effective amount of a peptide comprising the amino acid sequence defined in SEQ ID NO:5.
Dependencies are inferred from the claim text.